(3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride

(3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride - Names and Identifiers

Name	(R)-3-Quinuclidinol hydrochloride
Synonyms	(r)-3-quinuclidinol hcl (R)-3-QUINUCLIDINOL HCL 3-R-QUINUCLIDINOL HYDROCHLORIDE 3-r-quinuclidinol hydrochloride (r)-(-)-3-hydroxyquinuclidine hcl (R)-3-Quinuclidinol hydrochloride (R)-3-QUINUCLIDINOL HYDROCHLORIDE (r)-(-)-3-quinuclidinol hydrochloride (R)-(-)-3-QUINUCLIDINOL HYDROCHLORIDE (r)-3-hydroxyquinuclidine hydrochloride (R)-3-HYDROXYQUINUCLIDINE HYDROCHLORIDE r(-)-3-hydroxyquinuclidine hydrochloride R(-)-3-HYDROXYQUINUCLIDINE HYDROCHLORIDE (R)-(-)-3-Hydroxyguinuclidine hydrochloride (r)-(-)-3-hydroxyguinuclidine hydrochloride (r)-(-)-3-hydroxyquinuclidine hydrochloride (R)-1-AZABICYCLO[2.2.2]OCTAN-3-OL HYDROCHLORIDE (r)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride (3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride
CAS	42437-96-7
InChI	InChI=1/C7H13NO.ClH/c9-7-5-8-3-1-6(7)2-4-8;/h6-7,9H,1-5H2;1H/t7-;/m0./s1

(3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride - Physico-chemical Properties

Molecular Formula	C7H14ClNO
Molar Mass	163.65
Melting Point	344-350°C(lit.)
Boling Point	246.5°C at 760 mmHg
Specific Rotation(α)	-35 º (c=1% in H2O)
Flash Point	102.9°C
Vapor Presure	0.00444mmHg at 25°C
BRN	80123
Storage Condition	2-8℃
Physical and Chemical Properties	Melting point 344-350°C(lit.) specific optical rotation -35 ° (c = 1% in H2O)

(3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
FLUKA BRAND F CODES	10-34

(3R)-1-azabicyclo[2.2.2]octan-3-ol hydrochloride - Introduction

(R)-3-Quinuclidinol hydrochloride, also known as (R)-3-Quinuclidinol hydrochloride, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
(R)-3-Quinuclidinol hydrochloride is a white or off-white crystalline solid that is soluble in water. Its chemical formula is C7H15NO · HCl, molecular weight 163.66g/mol.

Use:
(R)-3-Quinuclidinol hydrochloride is widely used in chemical synthesis. It can be used as a chiral catalyst, pharmaceutical intermediate, and chiral building block in organic synthesis. In addition, it is often used in the synthesis of biologically active compounds.

Preparation Method:
(R)-3-Quinuclidinol hydrochloride is generally prepared by reacting quinine with sodium hydroxide to obtain quinuclidinol, and then reacting with hydrochloric acid to obtain hydrochloride. In this process, it is necessary to use appropriate solvents and reaction conditions for control.

Safety Information:
The use of (R)-3-Quinuclidinol hydrochloride requires attention to the general safety practices of chemicals. It should be protected from light and kept dry. In contact with the skin and eyes should be washed immediately with plenty of water. Wear suitable personal protective equipment such as protective gloves, glasses and protective clothing when using or handling the substance to avoid discomfort or injury. Observe appropriate safety practices and specifications during use and storage. If necessary, refer to the Safety Data Sheet (SDS) of the chemical for more detailed safety information.

Last Update：2024-04-09 20:52:54